Acyclovir renal failure mechanism

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Other preventive strategies that are obvious and should be followed whenever possible include avoiding concomitant use of nephrotoxic drugs, limiting contrast volume, avoiding repeated contrast exposure, and achieving hemodynamic stability before the test or procedure. Rapidly progressive acute renal failure due to acyclovir: PGs play a significant role in maintaining normal renal physiology.

Pathogenic Mechanisms

ACT Investigators Acetylcysteine for prevention of renal outcomes in patients undergoing coronary and peripheral vascular angiography: This cellular uptake happens via the copper transporter-1 and OCT2.

We will examine these in greater depth in later drug-specific discussions. Choose a single article, issue, or full-access subscription. Acyclovir dose should be reduced in patients with underlying renal insufficiency.

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Amphotericin B Fungizone; brand not available in the United States. Abdominal ultrasound indicated the presence of a small amount of fluid in the hepatorenal recess and around both kidneys.

Supplemental Content

Since antiretroviral therapy is generally lifelong, it is important for clinicians to be able to recognize the common nephrotoxic manifestations of these drugs. Most drugs found to cause nephrotoxicity exert toxic effects by one or more common pathogenic mechanisms.

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Am J Kidney Dis. Renal function generally returns to baseline provided the impairment is recognized early and the offending medication is discontinued.

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We had access to unique administrative databases that allowed us to answer a lot of questions that you might not be able to get from conventional observational or randomized control studies. Despite vomiting 4—5 times a day as a predisposing factor for prerenal failure in our patient, she was adequately hydrated and no clinical evidence of hypovolemia was observed. Adverse reactions associated with systemic polymyxin therapy.

Fill in your details below or click an icon to log in: VEGF inhibition and renal thrombotic microangiopathy. Want to use this article elsewhere? Acute renal failure related to intravenous acyclovir. In this example, both formulas indicate renal insufficiency, but the patient's medications most likely would not require a dose adjustment.

Carmustine Gliadelsemustine investigational.

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Effect of co-trimoxazole and sulfamethoxazole on serum creatinine in normal subjects. We thank Elizabeth Liz Wagel for revising the manuscript.