Mechanism of action Metoprolol is a beta-1 selective beta blocker. Patients with renal impairment The rate of elimination is insignificantly affected by renal function and therefore no dose adjustment is needed.
Find medicines with the same active ingredients Find medicines from the same company. Metoprolol Drug Class Back to Top. Before surgery, the anaesthesiologist must be informed that the patient takes beta blockers.
Sympathetic ganglion blockers, or other beta blockers Patients who are concomitantly receiving sympathetic ganglion blockers, or other beta blockers including in the form of eye drops must continue being monitored. In case of cardiac arrest after overdosage with a beta-blocker, cardiopulmonary resuscitation during several hours may be required.
The dose may be further increased or combined with nitrates. Blood pressure should be monitored and dosage adjustment of the antihypertensive be made if necessary. The effects of metoprolol and other antihypertensive drugs on blood pressure are usually additive. Metoprolol reduces or blocks the stimulating effect of catecholamines particularly released in case of physical or mental stress on the heart. Metoprolol was first made in Amiodarone has an extremely long half-life approximately 50 dayswhich means that interactions can occur a long time after discontinuation of the preparation.
The following undesirable effects have been reported during the course of clinical studies or have been reported after routine use. Disposition of Toxic Drugs and Chemicals in Man 8th ed. Journal of Medical Toxicology.
The injectable form is given directly into a vein IV by a healthcare professional. This is eerie to suddenly come upon this thread. Patients should be admitted to hospital and, generally, should be managed in an intensive care setting, with continuous monitoring of cardiac function, blood gases, and blood biochemistry.
Metoprolol has a short half-life of 3 to 7 hours, so is taken at least twice daily or as a slow-release preparation. Your answer is too short to be accepted.
In most cases the symptoms cleared when metoprolol treatment was withdrawn. Archived from the original on It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action.
It is sold in formulations that can be taken by mouth or given intravenously. Epinephrine A dozen reports exist in respect of severe hypertension and bradycardia in patients treated with non-selective beta-receptor blockers including pindolol and propanalolwho were administered epinephrine adrenaline.
Metabolism and nutrition disorders Weight gain. Even apparently well patients who have taken a small overdose should be closely observed for signs of poisoning for at least 4 hours. Reporting of suspected adverse reactions.
The FDA categorizes medications based on safety for use during pregnancy.