Post marketing cases of peripheral oedema and cardiac failure have also been reported in patients with concomitant use of pioglitazone and nonsteroidal anti-inflammatory drugs, including selective COX-2 inhibitors.
Tel Se desconoce si se secreta en la leche materna. Patients should be advised to adhere strictly to a calorie-controlled diet. How to take Pioglitazone 4. Generalmente puede seguir tomando otros medicamentos mientras tome los comprimidos de Actos.
Talk to your doctor before you start to take this medicine: Read the Medication Guide provided by your pharmacist before you start using pioglitazone and each time you get a refill.
What is Actos?
Pioglitazone is a diabetes drug thiazolidinedione-type, also called "glitazones" used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes.
Congestive heart failure events leading to hospitalization that occurred during the PROactive trial are summarized in Table 8.
Pioglitazone is present in rat milk; however due to species-specific differences in lactation physiologyanimal data may not reliably predict drug levels in human milk.
During a mean follow-up of The following additional side-effects have been experienced by some patients when pioglitazone was taken with other antidiabetic medicines:.
This medication is not recommended for people with certain types of heart failure. What Pioglitazone is and what it is used for 2.
To be eligible patients had to have had one or more of the following: You may need to read it again. There was no tumorigenic response in mice of either sex. Actos 45 mg tablets Each tablet contains 45 mg of pioglitazone as hydrochloride.
Steady state pharmacokinetics are similar in patients age 65 and over and young subjects. ACTOS decreases insulin resistance in the periphery and in the liver resulting in increased insulindependent glucose disposal and decreased hepatic glucose output.
A summary of the overall incidence and types of common adverse events reported in trials of ACTOS add-on to metformin is provided in Table 3. In Canada - Call your doctor for medical advice about side effects. Store at room temperature away from moisture, heat, and light. The estimated background risk of miscarriage for the indicated population is unknown.
If these symptoms occur, tell your doctor right away. Macular edema has been reported in postmarketing experience in diabetic patients who were taking ACTOS or another thiazolidinedione.