Azithromycin for legionnaires disease

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It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide. Conventional in vitro susceptibility methods in broth and agar have proven unreliable. Legionella infection Legionella pneumonia Gram negative rods Pneumonia Pontiac fever Atypical pneumonia Community-acquired pneumonia. Nine patients experienced a total of 11 treatment-related adverse events.

Subscribers log in here. Both intravenous and oral azithromycin were well tolerated by patients enrolled in the study.

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Medical Care

Add to My Bibliography. Cultures of blood, sputum and pleural effusion were negative. The mortality of community-acquired Legionnaires' disease ranges from 16 to 30 percent if untreated or treated with inactive antibiotics; the mortality for nosocomial Legionnaires' disease can approach 50 percent given the underlying illness of the patient [ 1 ].

Guidelines for the management of adults with community-acquired pneumonia: Please review our privacy policy. In a study of similar design, Sanchez et al. In conclusion, our results extend previous knowledge that azithromycin is safe and effective for the treatment of patients with legionnaires disease who have comorbid conditions and require hospitalization.

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Legionella pneumophila serogroup 1 pneumonia recurrence postbone marrow transplantation. East, Worthington, OH jplouffe columbus. Incidence of Legionella pneumophila in acute lower respiratory tract infections. See "Epidemiology and pathogenesis of Legionella infection" and "Clinical manifestations and diagnosis of Legionella infection". To continue reading this article, you must log in with your personal, hospital, or group practice subscription.

The radiologic manifestations of Legionnaire's disease.

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Literature review current through: Legionella species community-acquired pneumonia: Comparison of azithromycin and erythromycin in the treatment of atypical pneumonias. One patient died of a myocardial infarction on the second hospital day.

The choice of oral dosing was at the discretion of the investigator. Certain fluoroquinolones eg, levofloxacin, moxifloxacin are effective and are recommended for adults with severe disease. Twenty-five hospitalized patients with community-acquired pneumonia and a positive result of a L.